Nucleic acid encoding the .alpha. chain prodomains of inhibin an

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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536 2351, 536 235, 4352402, 4352523, 4353201, 435 694, 935 11, C12P 2102, C12N 1512, C12N 121, C12N 510

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053106610

ABSTRACT:
DNA encoding the prepro inhibin .alpha. and .beta. chains has been isolated. This DNA is ligated into expression vectors and used to transform host cells for the preparation of inhibin or activin. Also provided are prohormone domains and other inhibin .alpha. or .beta. chain derivatives having therapeutic or diagnostic interest. The compositions provided herein are useful in the manipulation of fertility in animals.

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