Nucleic acid encoding TGF-.beta. and its uses

Details Nucleic acid encoding TGF-.beta. and its uses Nucleic acid encoding TGF-.beta. and its uses

1992-03-04

1994-02-08

Martinell, James

Chemistry: molecular biology and microbiology

Spore forming or isolating process

435 694, 4352523, 4353201, 530 235, 530 2351, C12N 1500, C12N 1516

Patent

active

052847632

ABSTRACT:
Nucleic acid encoding TGF-.beta. has been isolated and cloned into vectors which are replicated in bacteria and expressed in eukaryotic cells. TGF-.beta. is recovered from transformed cultures for use in known therapeutic modalities. Nucleic acid encoding TGF-.beta. is useful in diagnosis and identification of TGF-.beta. clones.

REFERENCES:
patent: 4434094 (1984-02-01), Seyedin et al.
patent: 4601978 (1986-07-01), Karin
patent: 4627982 (1986-12-01), Seyedin et al.
patent: 4708948 (1987-11-01), Iwata et al.
patent: 4774228 (1988-09-01), Seyedin et al.
patent: 4774322 (1988-09-01), Seyedin et al.
patent: 4886747 (1989-12-01), Derynck et al.
patent: 5168051 (1992-12-01), Derynck et al.
Seeburg et al, Nature 270: 486 (1977).
D'Andrea et al, Nucleic Acids Res. 9: 3119 (1981).
Massague et al, J. Biol. Chem., 260: 2636 (1985).
Tacon et al, Molec. Gen. Genet. 177: 427 (1980).
Lawn et al, Cell 15: 1157 (1978).
Seyedin et al, J. Biol. Chem, 262: 1946-1949 (1987).
Massaque, J. Biol. Chem, 259: 9756 (1984).
Coutelle et al., Gene, 3: 113 (1978).
Todaro et al., PNAS, 77(9): 5258-5262 (1980).
Todaro et al., Cancer Res., 38: 4147-4154 (1978).
Sporn et al., Science, 219: 1329 (1983).
Twardzik et al., JNCI, 69(4): 793-798 (1982).
Fontana et al., J. Immunol., 132: 1837-1844 (1984).
Schwyzer and Fontana, J. Immunol., 134: 1003-1009 (1985).
Roberts et al, PNAS, 78: 5339-5343 (1981).
Roberts et al, Nature, 295: 417-419 (1982).
Hanks et al., Proc. Natl. Acad. Sci. USA, 85: 79-82 (1988).
Holley et al., Proc. Natl. Acad. Sci. USA, 77: 5989-5992 (1980).
Holley et al., Cell Bio. Int. Rep. 7: 525-526 (1983).
Frouk et al., PNAS, 80: 3676-3680 (1983).
Assoian et al., J. Biol. Chem., 258: 7155-7160 (1983).
Tucker et al., Science, 226: 705-707 (1984).
Shipley, et al., "Reversible Inhibition of Normal Human Prokeratinocyte Proliferation by Type beta Transforming Growth Factor-Growth Inhibitor in Serum-free Medium", Apr. 1986, pp. 2068-2071, Cancer Research 46.
Skolnik-David, et al., "Site of premature termination of late transcription of simian virus 40 DNA: Enhancement by 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole", pp. 2743-2747, May 1982, vol. 79, Proc. Natl. Acad. Sci. Biochemistry.
Sporn, et al., "Some Recent Advances in the Chemistry and Biology of Transforming Growth Factor-Beta", Sep. 1987, pp. 1039-1045, vol. 105, The Journal of Cell Biology.
Ullrich, et al., "Isolation of the human insulin-like growth factor I gene using a single synthetic DNA probe", 1984, pp. 361-364 vol. 3, No. 2, The EMBO Journal.
Wells, et al. "The Role of DNA Structure in Genetic Regulation", Jan. 1977, pp. 305-340, CRC Critical Reviews in Biochemistry.
Ten Dijke et al, Proc. Natl. Acad Sci: 85: 4715-4719 (1988).
Cheifetz et al, Cell, 48: 409-415 (1987).
Seyedin et al, Proc. Natl. Acad Sci, USA: 82: 2267-2271 (1985).
Derynck, et al. "Human transforming growth factor-beta complementary DNA sequence and expression in normal and transformed cells" Aug. 1985, pp. 701-705, Nature, vol. 316.
Fine, et al. "BSC-1 growth inhibitor transforms a mitrogenic stimulus into a hypertrophic stimuls for renal proximal tubular cells: Relationship to Na.sup.+ /H.sup.+ antiport activity", Sep. 1985, pp. 6163-6166, vol. 82, Proc. Natl. Acad. Sci. Cell Biology.
Guroff, Gordon "Structure of Transforming Growth Factors--Alpha and -beta and Their Precursors" Chapter 5, pp. 133-163, Oncogenes, Genes, and Growth Factors, A Wiley-Interscience Publication John Wiley & Sons, New York, 1987.
Itakura, et al. "Expression in Escherichia coli of a Chemically Synthesized Gene for the Hormone Somatostatin", Dec. 9, 1977, pp. 1056-1063, Science, vol. 198.
Kemp, et al. "Direct immunoassay for detecting Escherichia coli colonies that contain polypeptides encoded by cloned DNA segments", Jul. 1981, pp. 4520-3423, vol. 78, No. 7, Proc. Natl. Acad. Sci.
Kozak, Marilyn "Influence of mRNA Secondary Structure on Binding and Migration of 40S Ribosomal Subunits", Jan. 1980, pp. 79-90, vol. 19, Cell.
Looman, et al., "Influence of the codon following the AUG initiation codon on the expression of a modified lacZ gene in Escherichia coli", 1987, pp. 2489-2492, vol. 6, No. 8, The EMBO Journal.
Masui, et al., "Type beta transforming growth factor is the primary differentiation-inducing serum factor for normal human bronchial epithelial cells," Apr. 1986, pp. 2438-2442, vol. 83, Proc. Natl. Acad. Sci Cell Biology.
Roberts, et al., "Type beta transforming growth factor: A bifunctional regulator of cellular growth," Jan. 1985, pp. 119-123, vol. 82, Proc. Natl. Acad. Sci. Cell Biology.
Roberts, et al., "Transforming growth factors: Isolation of polypeptides from virally and chemically transformed cells by acid/ethanol extraction", Jun. 1980, pp. 3494-3498, vol. 77, No. 6, Proc. Natl. Acad. Sci. Cell Biology.
Saito, et al. "Activation of the c-myc gene translocation: A model for translational control", Dec. 1983, pp. 7476-7480, vol. 80, Proc. Natl. Acad. Sci. Biochemistry.
Seyedin, et al., "Cartilage-inducing Factor-A", May 5, 1986, pp. 5693-5695, vol. 261, No. 13, The Journal of Biological Chemistry.
Lewin, Gene Expression, 2: 148-153 (1974): (London: John Wiley & Sons, Ltd.).
Roberts et al., Biochemistry, 22: 5692 (1983).
Houghton et al., Nuc. Acids Res., 8(13): 2885 (1980).
Childs et al., PNAS, 79 (17): 5312-5316 (1982).
Anzano et al, Cancer Res., 42: 4776ff (1982).

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