Nucleic acid encoding tek receptor tyrosine kinase

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

4352402, 4352523, 43525411, 4353201, 435194, 536 235, C12N 1512, C12N 912

Patent

active

056817142

ABSTRACT:
Novel receptor tyrosine kinase protein and isoforms thereof which are expressed in cells of the endothelial lineage, and DNA segments encoding the novel protein and isoforms thereof are disclosed. Methods for identifying ligands which are capable of binding to the receptor protein and methods for screening for agonist or antagonist substances of the interaction of the protein and a ligand are also disclosed.

REFERENCES:
Dumont et al., Oncogene, vol. 7, 1471-1480, 1992.
Iwama et al., Biochem & Biophys. Res. Commun., vol. 195, 301-309, 1993.
Horita et al., Biochem. & Biophys. Res. Commun., vol. 189, 1747-1753, 1992.
Dumont et al., Oncogene, vol. 8, 1293-1301, 1993.
Sambrook et al., Molecular Cloning, A Lab. Manual, Sec. Edition vol. 3, pp. 16.10-16.30 and 17.2-17.28, Cold Spring Harbor Lab. Press 1989.
Kramer, H., Cagan, R.L. & Zipursky, S.L. (1991), Nature, 352, 207-212.
Schejter, E.D. & Shilo, B.-Z. (1989), Cell, 56, 1093-1104.
Geissler, E.N., Rayn, M.A. & Housman, D.E. (1988), Cell, 55, 185-192.
Chabot, B., Stephenson, D.A., Chapman, V.M., Besmer, P. & Bernstein, A. (1988), Nature, 335, 88-89.
Russell, E.S. (1979), Adv.Genet., 20, 357-459.
Dubreuil et al., (1990), Ann. N.Y. Acad. Sci., 599, 58-65.
Williams et al., (1990), Cell, 63, 167-174.
Copeland et al., (1990), Cell, 63, 175-183.
Flanagan, J.G. & Leder, P. (1990), Cell, 63, 185-194.
Stephenson et al., (1991), Proc. Natl. Acad. Sci. 88, 6-10.
Pawson, T. & Bernstein, A. (1991), Trends Gen., 6, 350-356.
Noden, D.M. (1988) Development, 103, 121-140.
Tomasi, V., Manica, F. & Spisni, E. (1990), BioFactors, 2, 213-217.
Maher, P.A. (1991), J.Cell. Biol., 112, 955-963.
Runyan et al., (1990), Cell Reg., 1, 301-313.
Rodrigues, G.A., Naujokas, M.A. & Park, M. (1991), Mol.Cell.Biol., 11, 2962-2970.
Tahira, T., Ishizaka, Y., Itoh, F., Sugimura, T. & Nagao, M. (1990), Oncogene, 5, 97-102.
Reid et al., 1990, Proc. Natl. Acad. Sci., 87, 1596-1600.
Bernard, O., Li, M. & Reid, H.H. (1991), Proc. Natl. Acad. Sci. USA, 88, 7625-7629.
Eisemann, A., Ahn, J.A., Graziani, G., Tronick, S.R. & Ron, D. (1991), Oncogene, 6, 1195-1202.
Fujita, H., Ohta, M., Kawasaki, T. & Itoh, N. (1991), Biochem. Biophis. Res. Comm., 174, 946-951.
Vu et al., (1989), Mol.Cell.Biol., 9, 4563-4567.
Pardanaud et al., (1987), Development, 100, 339-349.
Coffin, J.D. & Poole, T.J. (1988). Development, 102, 735-748.
Noden, D.M. (1989), Am. Rev. Respir. Dis., 140, 1097-1103.
Noden, D.M. (1990), Ann. N.Y. Acad. Sci., 1, 236-249.
Wagner, R.C. (1980). Adv.Microcirc., 9, 45-75.
Beddington, R.S.P. & Martin, P. (1989), Mol.Cell.Med., 6, 263-274.
Sadowski, I. et al., Mol. Cell. Biol. 6, 4396 (1986).
Koch et al., Science 252:668-674, 1991.
Moran et al., PNAS USA 87:8622, 1990.
Anderson et al., Science 250:979, 1990.
Muslin, A.J. & Williams, L.T. (1991). Development, 112, 1095-1101.
Hanks, S.K., Quinn, A.M. & Hunter, T. (1988), Science, 241, 42-52.
Takahashi, M. & Cooper, G.M. (1987). Mol. Cell. Biol., 7, 1378-1385.
Partanen et al., 1990, Proc. Natl. Acad. Sci., 87, 8913-8917.
Safran et al., (1990), Oncogene, 5, 635-643.
Dumont et al. Abstracts, 20th Annual Meeting J. of Cell Biochem. 15C, Jan. 24-Feb. 3, 1991, H105.
Dumont et al., J. of Cell Biochem. Supplement 16F, Apr. 3-16, 1992, W204.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Nucleic acid encoding tek receptor tyrosine kinase does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nucleic acid encoding tek receptor tyrosine kinase, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleic acid encoding tek receptor tyrosine kinase will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1025382

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.