Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2003-08-01
2009-02-03
Pak, Michael (Department: 1646)
Chemistry: molecular biology and microbiology
Vector, per se
C435S325000, C536S023100, C536S023500, C536S024100
Reexamination Certificate
active
07485455
ABSTRACT:
The present invention discloses four groups of SCN5A variants that represent the most common SCN5A variants in humans. A specific mutation in one of the variants has been shown to display a different phenotype in relation to a human heart disease than other variants and known human sodium channel α subunits with corresponding mutations. The present invention provides new tools to study mutations and to design or identify new diagnostic and treatment strategies or agents for sodium channel related diseases or conditions.
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Ackerman Michael J.
Makielski Jonathan C.
Ye Bin
Mayo Clinic Health Solutions
Pak Michael
Quarles & Brady LLP
Wisconsin Alumni Research Foundation
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