Nucleic acid encoding secreted Mac-2 binding glycoprotein

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

4352523, 43525411, 4353201, 435325, 536 235, 536 2431, C12N 1512

Patent

active

059653825

ABSTRACT:
A purified glycoprotein complex of over 1200 kD apparent native molecular weight having a sedimentation value of approximately 25S and having the ability to selectively bind human Mac-2 or interfere with PHA activation of lymphocytes, DNA sequences that encode the protein, and expression systems for expressing it, thus providing for medicaments that are useful for treating or diagnosing diseases, including cancer, infectious disease, and diseases of the immune system.

REFERENCES:
patent: 5298391 (1994-03-01), Iacobelli
patent: 5422265 (1995-06-01), Civelli et al.
Rosenberg et al., J. Biol. Chem., 266, 18731-18736, Oct. 1991.
Pierce et al., Eur. J. Biochem., 196, 177-184, 1991.
A. Aruffo, et al., Journal of Experimental Medicine (1991) 174:949-952.
T. Maniatis, et al., Molecular Cloning (1989) 2nd Edition 9.47-9.55.
Ulrich et al., J. Biol. Chem. (1994) 269(28):18401-18406.
Friedman et al., Proc. Natl. Acad. Sci. USA (1993) 90:6815-6819.
Natali et al., Cancer Research (1982) 42:583-589.
Iacobelli et al., Fed. of European Biochem. Soc. (1993) 319(1,2,):59-65.
Freeman et al., Proc. Nat'l. Acad. Sci., (87):8810-8814 (1990).
Matsumoto et al., Proc. Nat'l. Acad. Sci., (87):9133-9137 (1990).
Kodama et al., Nature, (343):531-535 (1990).
Woo et al., Journal of Biological Chemistry, (265):7097-7099 (1990).
Ho et al., J. Immunology, (128):1221-1228 (1982).
Cherayil et al., Proc. Nat'l. Acad. Sci., (87):7324-7328 (1990).
Jia et al., J. Biol. Chem., (263):6009-6011 (1988).
Oda et al., Gene, (99):279-283 (1991).
Newburg et al., Pediatric Research, (31):22-28 (1992).
Lonnerdal, American Journal of Clinical Nutrition, (42):1299-1317 (1985).
Sharon et al., Science, (246):227-246 (1989).
Dupuis et al., Can. J. Biochem. Cell. Biol., (63):932-940 (1985).
Drickamer, J. Biol. Chem., (263):9557-9560 (1988).
Holmgren et al., Infection and Immunity, (39):147-154 (1983).
Zajac et al., Journal of General Virology, (72):1667-1675 (1991).
Laegreid et al., Acta. Paediatr. Scand., (75):696-701 (1986).
Leffler et al., Journal of Biological Chemistry, (261):10119-10126 (1986.
Raz et al., Int. J. Cancer, (46):871-877 (1990).
Allan et al., Exptl. Cell. Res., (78): 271-278 (1973).
Alexander et al., Biochimica et Biophysica Acta, (512):350-364 (1978).
Frigeri et al., J. Immunology, (148):861-867 (1992).
Lasky et al., Cell, (69):927-938 (1992).
Koths, et al., J. Biol. Chem., (268):14245-14249 (1993).
Mierendorf et al., Methods in Ienzymology, vol. 152, pp. 458-469, 1987, Academic Press.
Rosenberg et al., 1991, J. Biol. Chem., 266, 18731.
Linsley et al., 1986, Biochemistry, 25, 2978.
Jacobs et al., 1985, Nature, 313, 806.
Phillips, "The Involucrin Gene of the Galago", J. Biol. Chem., (1990), 265(14):7804-7807.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Nucleic acid encoding secreted Mac-2 binding glycoprotein does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nucleic acid encoding secreted Mac-2 binding glycoprotein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleic acid encoding secreted Mac-2 binding glycoprotein will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-651105

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.