Nucleic Acid Encoding novel protein tyrosine kinase

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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435691, 435194, 4352523, 43525411, 4353201, 435325, C12N 1509, C12N 1552

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active

057056250

ABSTRACT:
A novel protein tyrosine kinase, JAK3, and a polynucleotide sequence encoding JAK3 polypeptide are disclosed herein. JAK3 is a new member of the JAK family of protein tyrosine kinases which are important in regulation of cellular proliferation and differentiation. Also disclosed are therapeutic methods utilizing JAK3 polypeptide and polynucleotide sequences.

REFERENCES:
Silvennoinen, Proc. Natl. Acad. Sci, vol. 90, pp 8429-8433, 1993.
Sambrook et al., Molecular Cloning, A Laboratory Manual Second Edition, vol.3, 16.2-16.30, 17.2-17.28 1989 Cold Spring Harbor Laboratory Press, CSH.

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