Nucleic acid encoding novel protein phosphotyrosine phosphatase

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 235, 435 691, 435196, 4352523, 43525411, 435325, C12N 1555, C12N 916

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059555920

ABSTRACT:
The present invention relates to PTP-D1, a member of the novel PTP-D subfamily of protein tyrosine phosphatases. The present invention is directed to isolated PTP-D1 protein, nucleic acid constructs encoding for PTP-D1, cells containing the nucleic acid constructs, and methods for production and identification of PTP-D1. Antibodies to PTP-D1 protein and methods for screening molecules which can bind to PTP-D1 protein or inhibit or stimulate the protein-tyrosine phosphatase enzymatic activity of PTP-D1, are also provided.

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