Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...
Reexamination Certificate
2005-04-14
2008-09-09
Saoud, Christine J (Department: 1647)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
C435S069100, C435S252300, C435S320100, C530S350000, C536S023500
Reexamination Certificate
active
07422898
ABSTRACT:
There are provided non-human primate and rat GPR103 genes and proteins and a compound evaluation method employing the genes or proteins. There are also provided highly useful novel ligands for functional analysis of the GPR103 genes and proteins and for the compound evaluation. The nucleic acids or proteins having the sequences listed as SEQ ID NOS: 1 to 4 provide non-human primate or rat GPR103 genes and proteins and information based on the genes and proteins. The genes and proteins can be used for evaluation of compounds. The nucleic acids or proteins having the sequence listed as SEQ ID NO: 5 or 6 provide a GPR103 ligand.
REFERENCES:
patent: 6927041 (2005-08-01), Zhelnin et al.
patent: 2004/0248790 (2004-12-01), Hinuma et al.
patent: 1 207 201 (2002-05-01), None
patent: WO 00/11015 (2000-03-01), None
patent: WO 02/42458 (2002-05-01), None
Baribault et al., “The G-Protein-Coupled Receptor GPR103 Regulates Bone Formation”, Molecular and Cellular Biology, vol. 26(2), pp. 709-717 (2006).
Bruzzone et al., “Anatomical distribution and biochemical characterization of the novel RFamide peptide 26RFa in the human hypothalamus and spinal cord”, Journal of Neurochemistry, vol. 99, pp. 616-627 (2006).
Chartrel et al., “Identification of 26RFa, a hypothalamic neuropeptide of the RFamide peptide family with orexigenic activity”, PNAS, vol. 100(25), pp. 15247-15252 (2003).
do Rego et al., “Behavorial effects of 26RFamide and related peptides”, Peptides, vol. 27, pp. 2715-2721 (2006).
Fukusumi et al., “A New Peptide Ligand and Its Receptor Regulating Adrenal Function in Rats”, The Journal of Biological Chemistry, vol. 278(47), pp. 46387-46395 (2003).
Jiang et al., “Identification and Characterization of a Novel RF-amide Peptide Ligand for Orphan G-protein-coupled Receptor SP9155”, The Journal of Biological Chemistry, vol. 278(30), pp. 27652-27657 (2003).
Kampe et al., “Effect of central administration of QRFP(26) peptide on energy balance and characterization of a second QRFP receptor in rat”, Brain Research, vol. 1119, pp. 133-149 (2006).
Lee et al., “Discovery and mapping of ten novel G protein-coupled receptor genes”, Gene, vol. 275, pp. 83-91 (2001).
Moriya et al., “RFamide Peptide QRFP43 Causes Obesity with Hyperphagia and Reduced Thermogensis in Mice”, Endocrinology, vol. 147(6), pp. 2916-2922 (2006).
Navarro et al., “Novel role of 26RFa, a hypothalamic RFamide orexigenic peptide, as putative regulator of the gonadotropic axis”, J. Physiol., vol. 573.1, pp. 237-249 (2006).
Takayasu et al., “A neuropeptide ligand of the G protein-coupled receptor GPR103 regulates feedings, behavioral arousal, and blood pressure in mice”, PNAS, vol. 103(19), pp. 7438-7743 (2006).
Thuau et al., “Structural studies on 26RFa, a novel RFamide-related peptide with orexigenic activity”, Peptides, vol. 26, pp. 779-789 (2005).
Iwaasa Hisashi
Mashiko Satoshi
Sano Hideki
Banyu Pharmaceutical Co. Ltd.
Daniel Mark R.
Lockard Jon M
Saoud Christine J
Struse Heidi M.
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