Nucleic acid encoding mammalian UBR1

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

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4353201, 4352523, 536 235, C12N 1512, C12N 1563, C12N 510, C12N 121

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058613129

ABSTRACT:
Disclosed here is a nucleic acid sequence encoding a recognition component of the N-end rule pathway. This nucleic acid sequence is characterized by the ability to specifically hybridize to the nucleic acid sequence of SEQ ID NO 1 under stringent hybridization conditions. Such conditions are defined below. Also disclosed is a nucleic acid sequence encoding a recognition component of the N-end rule pathway which is characterized by the ability to specifically hybridize to the nucleic acid sequence of SEQ ID NO 2 under stringent hybridization conditions. Also disclosed are DNA expression vectors containing nucleic acid sequences of the type described above, as well as cells transformed with such expression vectors. Further disclosed are applications for the compositions described above.

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