Nucleic acid encoding greA from Streptococcus pneumoniae

Details Nucleic acid encoding greA from Streptococcus pneumoniae Nucleic acid encoding greA from Streptococcus pneumoniae

1997-01-23

2000-02-08

Duffy, Patricia A.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 697, 4352523, 43525411, 4353201, 435325, 536 232, 536 234, 536 237, 935 3, 935 6, 935 12, C12P 2104, C12N 1500, C07H 2104

Patent

active

060227109

ABSTRACT:
greA polypeptides and DNA (RNA) encoding such greA and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such greA for the treatment of infection, particularly bacterial infections. Antagonists against such greA and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of greA nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding greA/greB gene family and for detecting the polypeptide in a host.

REFERENCES:
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