Nucleic acid encoding fluorescent protein constructs and...

Details Nucleic acid encoding fluorescent protein constructs and... Nucleic acid encoding fluorescent protein constructs and...

2008-04-08

2008-04-08

Robinson, Hope (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S007100, C435S252300, C435S325000, C435S320100, C435S007200, C435S007400, C530S300000, C530S350000, C424S192100, C536S023100

Reexamination Certificate

active

07354735

ABSTRACT:
Isolated nucleic acids encoding a fluorescent protein construct that detect apoptosis are disclosed. The isolated nucleic acids contain a donor-acceptor pair of green fluorescent proteins and a peptide linker containing a substrate sequence encoding a cleavage site of a caspase. The linker is flanked with at least one glycine pair. Expression constructs, isolated host cells and gene delivery vehicles containing these isolated nucleic acids are also disclosed.

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