Nucleic acid encoding a self-assembling split-fluorescent...

Details Nucleic acid encoding a self-assembling split-fluorescent... Nucleic acid encoding a self-assembling split-fluorescent...

2011-06-07

2011-06-07

Robinson, Hope A (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S006120, C435S252000, C435S325000, C435S320100

Reexamination Certificate

active

07955821

ABSTRACT:
The invention provides a protein labeling and detection system based on self-complementing fragments of fluorescent and chromophoric proteins. The system of the invention is exemplified with various combinations of self-complementing fragments derived fromAequorea victoriaGreen Fluorescent Protein (GFP), which are used to detect and quantify protein solubility in multiple assay formats, both in vitro and in vivo.

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