Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2005-03-29
2005-03-29
Myers, Carla J. (Department: 1637)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S022100, C536S023100, C536S023200, C536S023500, C536S023700, C536S024330, C536S024500, C435S006120, C435S091520, C435S091530, C435S194000, C435S325000, C435S810000
Reexamination Certificate
active
06872816
ABSTRACT:
The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof. The present invention further relates to methods and devices for the separation of nucleic acid molecules based on charge. The present invention also provides methods for the detection of non-target cleavage products via the formation of a complete and activated protein binding region. The invention further provides sensitive and specific methods for the detection of nucleic acid from various viruses in a sample.
REFERENCES:
patent: 4511502 (1985-04-01), Builder et al.
patent: 4511503 (1985-04-01), Olson et al.
patent: 4512922 (1985-04-01), Jones et al.
patent: 4518526 (1985-05-01), Olson
patent: 4683194 (1987-07-01), Saiki et al.
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4683202 (1987-07-01), Mullis
patent: 4775619 (1988-10-01), Urdea
patent: 4818680 (1989-04-01), Collins et al.
patent: 4876187 (1989-10-01), Duck et al.
patent: 5011769 (1991-04-01), Duck et al.
patent: 5030557 (1991-07-01), Hogan et al.
patent: 5108892 (1992-04-01), Burke et al.
patent: 5118605 (1992-06-01), Urdea
patent: 5144019 (1992-09-01), Rossi
patent: 5210015 (1993-05-01), Gelfand et al.
patent: 5380833 (1995-01-01), Urdea
patent: 5403711 (1995-04-01), Walder et al.
patent: 5407795 (1995-04-01), Kolberg et al.
patent: 5422253 (1995-06-01), Dahlberg et al.
patent: 5427930 (1995-06-01), Birkenmeyer et al.
patent: 5487972 (1996-01-01), Gelfand et al.
patent: 5494810 (1996-02-01), Barany et al.
patent: 5516663 (1996-05-01), Backman et al.
patent: 5541311 (1996-07-01), Dahlberg et al.
patent: 5545729 (1996-08-01), Goodchild et al.
patent: 5601976 (1997-02-01), Yamane et al.
patent: 5614402 (1997-03-01), Dahlberg et al.
patent: 5660988 (1997-08-01), Duck et al.
patent: 5691142 (1997-11-01), Dahlberg et al.
patent: 5698400 (1997-12-01), Cotton et al.
patent: 5719028 (1998-02-01), Dahlberg et al.
patent: 5783392 (1998-07-01), Seibl et al.
patent: 5792614 (1998-08-01), Western et al.
patent: 5795763 (1998-08-01), Dahlberg et al.
patent: 5830664 (1998-11-01), Rosemeyer et al.
patent: 5837450 (1998-11-01), Dahlberg et al.
patent: 5843654 (1998-12-01), Heisler et al.
patent: 5843669 (1998-12-01), Kaiser et al.
patent: 5846717 (1998-12-01), Brow et al.
patent: 5874283 (1999-02-01), Harrington et al.
patent: 5882867 (1999-03-01), Ullman et al.
patent: 5888780 (1999-03-01), Dahlberg et al.
patent: 5985557 (1999-11-01), Prudent et al.
patent: 5994069 (1999-11-01), Hall et al.
patent: 6001567 (1999-12-01), Brow et al.
patent: 6090543 (2000-07-01), Prudent et al.
patent: 6090606 (2000-07-01), Kaiser et al.
patent: 0 411 186 (1991-02-01), None
patent: 0 482 714 (1991-10-01), None
patent: 8909284 (1989-10-01), None
patent: 9001069 (1990-02-01), None
patent: 9015157 (1990-12-01), None
patent: 9109950 (1991-07-01), None
patent: 9202638 (1992-02-01), None
patent: 9206200 (1992-04-01), None
patent: 9429482 (1994-12-01), None
patent: 9514106 (1995-05-01), None
patent: 9620287 (1996-07-01), None
patent: 9640999 (1996-12-01), None
Harrington, J. (Diss. Abstr. Int. B (1995) 55(7): 2539).*
Biochemical, Reagent kits offer Scientists good return on Investment. The Scientist, vol. 9, No. 15, pp. 1-5.*
Lyamichev et al. Structure-Specific Endonucleotlytic cleavage of nucleic acids by Eubacterial DNA polymerases. Science, vol. 260, pp. 778-783, May 1993.*
Nolan et al. Kinetic Analysis of Human Flap endonucleases-1 by Flow cytometry. Biochemistry, vol. 35, pp. 11668-11676, Aug. 1996.*
Harington et al. The characterization of a mammalian DNA-structure-specific endonuclease. The EMBO Journal, vol. 13, No. 6, pp. 1235-1246, Dec. 1994.*
Biochemical, Reagent kits offer Scientists good return on Investment. The Scientist, vol. 9, No. 15, pp. 1-5, Jul. 1995.*
Abrams et al., “Comprehensive Detection of Single Base Changes in Human Genomic DNA Using Denaturing Gradient Gel Electrophoresis and a GC Clamp,”Genomics7:463-475 (1990).
Akhmetzjanov and Vakhitov, “Molecular cloning and nucleotide sequence of the DNA polymerase gene fromThermus flavus,” Nucl. Acids Res.20:5839 (1992).
Altamirano et al., “Identification of Hepatitis C Virus Genotypes among Hospitalized Patients in British Columbia, Canada,”J. Infect. Dis.171:1034-1038 (1995).
Anderson and Young, “Quantitative Filter Hybridization”, inNucleic Acid Hybridization, Eds Hames & Higgins, IRL Press, Washington, DC, pp. 73-111 (1985).
Electrophoresis, 2nd Edition, ed. Anthony T. Andrews, Clarendon Press, New York, New York (1986), pp. 153-154.
Antao et al. “A thermodynamic study of unusally stable RNA and DNA hairpins,”Nucl. Acids Res.19:5901-5905 (1991).
Bambara et al., “Enzymes and Reactions at the Eukaryotic DNA Replication Fork,”J. Biol. Chem.272:4647-4650 (1997).
Barany, “Genetic disease detection and DNA amplification using cloned thermstable ligase,”Proc. Natl. Acad. Sci., 88:189-193 (1991).
Barany, “The Ligase Chain Reaction in a PCR World,”PCR Methods and Applic., 1:5-16 (1991).
Bardwell et al., “Specific Cleavage of Model Recombination and Repair Intermediates by the Yeast Rad1-Rad10 DNA Endonuclease,”Science265:2082-2085 (1994).
Barnes et al., “Mechanism of Tracking and Cleavage of Adduct-damaged DNA Substrates by the Mammalian 5′ -to 3′Exonuclease/Endonuclease RAD2 Homologue 1 or Flap Endonuclease 1”,J. Biol. Chem.271:29624-29632 (1996).
Bergseid et al., “A High Fidelity Thermostable DNA Polymerase Isolated fromPyrococcus furiosus,” Strategies4:34-35 (1991).
Bhagwat et al., “The 5′-Exonuclease Activity of Bacteriophage T4 RNase H is Stimulated by the T4 Gene 32 Single-stranded DNA-binding Protein, but Its Flap Endonuclease Is Inhibited,”J. Biol. Chem.272:28523-28530 (1997).
Bonch-Osmolovslaya, et al.,Microbiology(Engl. Transl. of Mikrobiologiya) 57:78-85 (1988).
Brutlag et al., “An Active Fragment of DNA Polymerase Produced By Proteolytic Cleavage,”Biochem. Biophys. Res. Commun.37:982-989 (1969).
Brow et al., “Differentiation of Bacterial 16S rRNA Genes and Intergenic Regions andMycobacterium tuberculosis katGGenes by Structure-Specific Endonuclease Cleavage,”J. of Clin Micro.34:3129-3137 (1996).
Carballeira et al., “Purification of a Thermostable DNA Polymerase fromThermus thermophilusHB8, Useful in the Polymerase Chain Reaction,”Biotechniques9:276-281 (1990).
Ceska et al., “A helical arch allowing single-stranded DNA to thread through T5 5′-exonuclease,”Nature382:90-93 (1996).
Ceska et al., “Structure-specific DNA cleavage by 5′ nucleases,”TIPS 23(1998).
Copley and Boot, “Exonuclease Cycling Assay: An Amplified Assay for the Detection of Specific DNA Sequences,”BioTechniques13:888-891 (1992).
Cuthbert, “Hepatitis C:Progress and Problems,”Clin. Microbiol. Rev.7:505-532 (1994).
DeMott et al., “Human RAD2 Homolog 1 5′-3′-Exo/Endonuclease Can Efficiently Excise a Displasced DNA Fragment Containing a 5′-Terminal Abasic Lesion by Endonuclease Activity,”J. Biol. Chem.271:30068-30076 (1996).
Doty et al., “Strand Separation and Specific Recombination in Deoxyribonucleic Acids: Physical Chemical Studies,”Proc. Natl. Acad. Sci. USA46:461-476 (1996).
Duck et al., “Probe Amplifier System Based on Chimeric Cycling Oligonucleotides,”BioTech., 9:142-147 (1990).
Dunn et al., “Complete Nucleotide Sequence of Bacteriophage T7 DNA and the Locations of T7 Genetic Elemen
Brow Mary Ann D.
Hall Jeff G.
Kwiatkowski Robert W.
Lyamichev Victor I.
Mast Andrea L.
Medlen & Carroll LLP
Myers Carla J.
Spiegler Alexander H.
Third Wave Technologies Inc.
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