Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Reexamination Certificate
2004-09-03
2010-12-07
Calamita, Heather (Department: 1637)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
C536S024300
Reexamination Certificate
active
07846693
ABSTRACT:
A method for determining the methylation status of a potential methylation site in genomic nucleic acid comprising treating genomic nucleic acid with an agent which modifies cytosine bases but does not modify 5methyl-cytosine bases under conditions to form a. modified nucleic acid template containing a potential methylation site; providing a first clamp containing a first capture sequence complementary to a region flanking one side of the potential methylation site in the modified nucleic acid template, providing a second clamp containing a second capture sequence complementary to a region flanking the other side of the potential methylation site in the modified nucleic acid template; allowing the first clamp and the second clamp to hybridise to the modified nucleic acid template; ligating the hybridised first and second clamps to form a probe spanning the potential methylation site in the modified nucleic acid template; digesting the modified nucleic acid template to obtain the probe; and detecting the probe and determining the methylation status of the potential methylation site in the modified genomic nucleic acid.
REFERENCES:
patent: 5629156 (1997-05-01), Shah et al.
patent: 5750338 (1998-05-01), Collins et al.
patent: 5786146 (1998-07-01), Herman et al.
patent: 5824517 (1998-10-01), Cleuziat et al.
patent: 5952174 (1999-09-01), Nikiforov et al.
patent: 6156501 (2000-12-01), McGall et al.
patent: 6251637 (2001-06-01), Blusch
patent: 6265171 (2001-07-01), Herman et al.
patent: 6331393 (2001-12-01), Laird et al.
patent: 6692918 (2004-02-01), Kurn
patent: 6960436 (2005-11-01), Cottrell
patent: 7008770 (2006-03-01), Berlin
patent: 7288373 (2007-10-01), Millar et al.
patent: 7413855 (2008-08-01), Bergmann et al.
patent: 7504207 (2009-03-01), Bergquist
patent: 2002/0086324 (2002-07-01), Laird et al.
patent: 2002/0142397 (2002-10-01), Collas et al.
patent: 2003/0073081 (2003-04-01), Mukai et al.
patent: 2003/0082600 (2003-05-01), Olek et al.
patent: 2003/0119025 (2003-06-01), Olek et al.
patent: 2003/0143577 (2003-07-01), Hogrefe et al.
patent: 2004/0067559 (2004-04-01), McCarthy et al.
patent: 2004/0086944 (2004-05-01), Grigg et al.
patent: 2004/0203004 (2004-10-01), Bernard et al.
patent: 2004/0219539 (2004-11-01), Millar et al.
patent: 2005/0019762 (2005-01-01), Olek
patent: 2005/0059003 (2005-03-01), Enoki et al.
patent: 2005/0118578 (2005-06-01), Mineno et al.
patent: 2005/0202490 (2005-09-01), Makarov
patent: 2006/0014144 (2006-01-01), Christensen et al.
patent: 2006/0051771 (2006-03-01), Murphy et al.
patent: 2006/0166203 (2006-07-01), Took
patent: 2006/0286576 (2006-12-01), Lofton-Day
patent: 2007/0020633 (2007-01-01), Millar
patent: 2007/0020639 (2007-01-01), Shapero
patent: 2007/0020653 (2007-01-01), Holliger
patent: 2007/0026070 (2007-02-01), Vonwiller
patent: 2007/0042365 (2007-02-01), Millar et al.
patent: 2007/0065824 (2007-03-01), Gutig
patent: 2007/0178457 (2007-08-01), Millar
patent: 2007/0190530 (2007-08-01), Birkner et al.
patent: 2007/0264653 (2007-11-01), Berlin et al.
patent: 2008/0050738 (2008-02-01), Millar
patent: 2009/0029346 (2009-01-01), Millar et al.
patent: 2009/0042732 (2009-02-01), Millar
patent: 2009/0130657 (2009-05-01), Millar
patent: 2009/0263909 (2009-10-01), Millar
patent: 2010/0041013 (2010-02-01), Millar et al.
patent: 2010/0092972 (2010-04-01), Millar et al.
patent: 103 31 107 (2004-12-01), None
patent: 1 130 113 (2001-09-01), None
patent: 1 319 718 (2003-06-01), None
patent: 1443052 (2004-08-01), None
patent: 1 801 213 (2007-06-01), None
patent: WO 95/01456 (1995-01-01), None
patent: WO 95/22623 (1995-08-01), None
patent: WO 97/41254 (1997-11-01), None
patent: WO 97/45559 (1997-12-01), None
patent: WO 98/20157 (1998-05-01), None
patent: WO 98/29108 (1998-07-01), None
patent: WO 99/09211 (1999-02-01), None
patent: WO 99/14226 (1999-03-01), None
patent: WO 99/49081 (1999-09-01), None
patent: WO 00/44934 (2000-08-01), None
patent: WO 00/50869 (2000-08-01), None
patent: WO 01/09374 (2001-02-01), None
patent: WO 01/38565 (2001-05-01), None
patent: WO 01/42493 (2001-06-01), None
patent: WO 01/76451 (2001-10-01), None
patent: WO 02/36821 (2002-05-01), None
patent: WO 02/38801 (2002-05-01), None
patent: WO 02/46452 (2002-06-01), None
patent: WO 02/072880 (2002-09-01), None
patent: WO 02/097065 (2002-12-01), None
patent: WO 2003/008623 (2003-01-01), None
patent: WO 2003/048732 (2003-06-01), None
patent: WO 2003/051901 (2003-06-01), None
patent: WO 2003/052132 (2003-06-01), None
patent: WO 2003/052133 (2003-06-01), None
patent: WO 2003/052134 (2003-06-01), None
patent: WO 2004/015139 (2004-02-01), None
patent: WO 2004/065625 (2004-08-01), None
patent: WO 2004/090166 (2004-10-01), None
patent: WO 2004/096825 (2004-11-01), None
patent: WO 2004/111266 (2004-12-01), None
patent: WO 2005/021778 (2005-03-01), None
patent: WO 2005/056790 (2005-06-01), None
patent: WO 2006/058393 (2006-06-01), None
patent: WO 2006/066353 (2006-06-01), None
patent: WO 2006/113770 (2006-10-01), None
patent: WO 2007/106802 (2007-09-01), None
patent: WO 2008/109945 (2008-09-01), None
patent: WO 2008/135512 (2008-11-01), None
patent: WO 2009/067743 (2009-06-01), None
patent: WO 2009/070843 (2009-06-01), None
patent: WO 2009/079703 (2009-07-01), None
Badal Sushma et al.: “The human papillomavirus-18 genome is efficiently targeted by cellular DNA methylation” VIROLOGY, vol. 324, No. 2, Jul. 1, 2004, pp. 483-492.
Badal V. et al.: “CpG methylation of human papillomavirus type 16 DNA in cervical cancer cell lines and in clinical specimens: Genomic hypomethylation correlates with carcinogenic progression” Journal Of Virology, The American Society For Microbiology, US, vol. 77, No. 11, Jun. 1, 2003, pp. 6227-6234.
Baleriola C et al.: “Comparison of a novel HPV test with the Hybrid Capture II (hcll) and a reference PCR method shows high specificity and positive predictive value for 13 high-risk human papillomavirus infections” Journal of Clinical Virology, Elsevier, Amsterdam, NL, vol. 42, No. 1, May 1, 2008, pp. 22-26.
Extended European Search Report issued in corresponding European Application No. 05821631.8, dated Nov. 7, 2008.
Feng et al: “Detection of hypermethylated genes in women with and without cervical neoplasia.” Journal of the National Cancer Institute Feb. 16, 2005, vol. 97, No. 4, pp. 273-282.
Gu W. et al, Depletion ofSaccharomyces cerevisiaetRNAHis Guanylyltransferase Thglp leads to uncharged tRNAH is with additional m5C, Mol Cell Biol. Sep. 2005; vol. 25, No. 18, pp. 8191-8201.
International Search Report issued for corresponding PCT Application No. PCT/AU2006/000755, dated Aug. 30, 2006.
International Search Report issued on corresponding PCT Application No. PCT/AU2008/000367, dated May 14, 2008.
Kalantari, Mina et al. “Conserved methylation patterns of human papillomavirus type 16 DNA in asymptomatic infection and cervical neoplasia,” Journal of Virology, vol. 78, No. 23, Dec. 2004, pp. 12762-12772.
Kim T Y et al: “DNA hypermethylation in gastric cancer” Alimentary Pharmacology & Therapeutics, vol. 20, No. Suppl. 1, Jul. 2004, pp. 131-142.
Kozak et al.: “Influence of secondary structure on binding and migration of 40S ribosomal subunits,” Cell, vol. 19, 1980, pp. 79-90.
Malyukova A V et al: “Methylation of the Putative Tumor Suppressor Gene RASSF1A in Primary Cervical Tumors” Molecular Biology, Kluwer Academic Publishers-Plenum Publishers, NE, vol. 38, No. 6, Nov. 1, 2004, pp. 857-864.
Narayan Gopeshwar et al: “Frequent Promoter Methylation of CDH1, DAPK, RARB, and HIC1 Genes in Carcinoma of Cervix Uteri: Its Relationship to Clinical Outcome” Molecular Cancer, Biomed Central, London, GB, vol. 2, No. 1, May 13, 2003, p. 24.
Nilsson et al., “Padlock Probes: Circularizing Oligonucleotides for localized DNA Detection”, Science; 265:2085-2088 (1994).
Nousbaum, J. et al., “Prospective Characteristics of Full-Length Hepatitis C Virus NS5A Quasispecies during Induction and Combination Antiviral Therapy,” Journal of Vir
Gabor Miklos George L.
Melki John Robert
Millar Douglas Spencer
Calamita Heather
Human Genetic Signatures Pty. Ltd.
Knobbe Martens Olson & Bear LLP
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