Nucleic acid delivery system, methods of synthesis and use...

Details Nucleic acid delivery system, methods of synthesis and use... Nucleic acid delivery system, methods of synthesis and use...

2007-03-06

2007-03-06

Woitach, Joseph (Department: 1632)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C536S023400, C536S023530, C530S350000, C530S402000, C424S178100

Reexamination Certificate

active

08822033

ABSTRACT:
A nucleic acid delivery system is described. The delivery system contains a fusion protein having a target moiety and a nucleic acid binding moiety, and a nucleic acid sequence bound to the nucleic acid binding moiety of the fusion protein. The target moiety can be an antibody or a ligand. The use of this nucleic acid delivery system to transienntly or stably express a desired nucleic acid sequence in a cell is disclosed. Also disclosed is the use of this delivery system to target a cell and deliver a desired product.

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Kabanov, A., et al., Journal of Controlled Release 28:15-35 (Jan. 1994).

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