Nucleic acid capture method

Details Nucleic acid capture method Nucleic acid capture method

1989-09-29

1990-05-01

Nucker, Christine M.

Chemistry: molecular biology and microbiology

Process of utilizing an enzyme or micro-organism to destroy...

Treating animal or plant material or micro-organism

435 6, 436178, 436501, 436526, 935 19, 935 85, C12N 108

Patent

active

049218050

ABSTRACT:
A nucleic acid capture reagent which comprises one or more molecules that are capable of intercalation into nucleic acids and are attached to a solid support via a molecular linker. This capture reagent is useful for the separation and isolation of nucleic acids from complex unpurified biological solutions such as serum, sputum, blood, and urine. The resulting capture reagent-nucleic acid complexes are easily isolated from the sample solution by mechanical or magnetic means and the bound nucleic acids are released by simple chemical treatment.

REFERENCES:
patent: 4119521 (1978-10-01), Chirikjian
patent: 4563417 (1986-01-01), Albarella et al.
patent: 4599303 (1986-07-01), Yabusaki et al.
patent: 4665184 (1987-12-01), Dervan et al.
Sharp, P. A. et al., Biochemistry 12: 3055-3063 (1973).
Dervan et al., J. Amer. Chem. Soc., 100: 1968-1970 (1978).
Vacek, A. T. et al., Anal. Biochem., 124: 414-420 (1982).
Thomas, K. A. et al., Anal. Biochem., 91: 209-223 (1978).
Dervan and Becker, J. Amer. Chem. Soc., 100:6 (1978).
Kimberly and Goldstein, Anal. Chem., 53:789 (1981).
Barry et al., J. Chem. Soc. (Dalton Trans.), p. 2086 (1974).

Affiliated with

Also associated with

Rating

Nucleic acid capture method does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nucleic acid capture method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleic acid capture method will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-829261