Nucleic acid base sequence determining method and inspecting...

Details Nucleic acid base sequence determining method and inspecting... Nucleic acid base sequence determining method and inspecting...

2002-12-10

2010-02-09

Clow, Lori A (Department: 1631)

Data processing: measuring, calibrating, or testing

Measurement system in a specific environment

Biological or biochemical

C702S019000

Reexamination Certificate

active

07660676

ABSTRACT:
When the nucleic-acid base sequence of A, C, G, and T (or U) is determined by interpreting fluorescent-light intensity waveform data acquired by measuring nucleic-acid fragments, it is desirable to determine, with a high-accuracy, the base sequence at a location at which the data interpretation is difficult. In order to accomplish this object, the data interpretation is performed by making reference to information acquired by performing the statistical processing to plural pieces of fluorescent-light intensity waveform data corresponding to already-known base sequences. This method allows the determination of the nucleic-acid base sequence at the above-described location.

REFERENCES:
patent: 4-294257 (1991-03-01), None
patent: 05-322771 (1993-07-01), None
patent: WO 99/57547 (1999-04-01), None
Ewing et al. (Genome Research (1998) vol. 8, pp. 175-185; p. 176, col. 2 to p. 177, col. 1).
Inazuka et al. (Genome Methods (1997) vol. 7, pp. 1094-1103).

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