Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Ultrasound contrast agent
Patent
1996-06-05
1999-04-27
Dees, Jose G.
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Ultrasound contrast agent
424 95, A61K 4904
Patent
active
058978518
ABSTRACT:
A method of activating an ultrasound contrast agent such that an increased number of microbubbles are produced and subsequent ultrasound images using the activated agent is enhanced. Hypobaric methods are disclosed which provide significant increases in bubble population per unit volume over unactivated solutions. The method is particularly useful for the activation of the dispersed phase in a gas or liquid in liquid emulsion.
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Kessler Dean R.
Quay Steven C.
Roy Ronald A.
Worah Dilip
Dees Jos,e G.
Hartley Michael G.
Sonus Pharmaceuticals Inc.
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