Nuclease-resistant hydrophilic complex of polyriboinosinic-polyr

Details Nuclease-resistant hydrophilic complex of polyriboinosinic-polyr Nuclease-resistant hydrophilic complex of polyriboinosinic-polyr

1980-11-18

1982-09-14

Hazel, Blondel

Drug, bio-affecting and body treating compositions

Lymphokine

2601125R, 424177, 424180, 536 27, 536 28, 536 29, A61K 4502, A61K 3702, C07C10352

Patent

active

043495389

ABSTRACT:
A nuclease-resistant hydrophilic complex of polyriboinosinic-polyribocytidylic acid, poly-1-lysine, and carboxymethylcellulose, and injectable preparations thereof in a pharmaceutically acceptable aqueous carrier such as saline solution. When administered to a human or non-human primate host, the complex is effective in inducing the synthesis in such host of antiviral levels of interferon.

REFERENCES:
patent: 4024241 (1977-05-01), Levy
Chemical Abstracts, vol. 92, Abstract No. 174365n, p. 37, 1980.
Chemical Abstracts, vol. 92, Abstract No. 104368s, p. 57, 1980.
Chemical Abstracts, vol. 93, Abstract No. 197823v, p. 61, 1980.
Chemical Abstracts, vol. 91, Abstract No. 321y, p. 319 1979.
Chemical Abstracts, vol. 92, Abstract No. 600v, p. 596, 1980.
Derwent Abstracts, Belgium Pat. No. 833838, 1976.

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