Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...
Patent
1974-09-27
1976-04-20
Gotts, Lewis
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Reduced antigenicity, reduced ability to bind complement, or...
2601125R, 2602115R, 260231CM, 424180, 424361, 424362, A61K 3700, C07C10352, C07H 1900
Patent
active
039520978
ABSTRACT:
A nuclease-resistant hydrophilic complex of polyriboinosinic-polyribocytidylic acid, poly-1-lysine and carboxymethylcellulose, and injectable preparations thereof in a pharmaceutically acceptable aqueous carrier such as saline solution. When administered to a non-human primate host, the complex is effective in inducing the synthesis in such host of antiviral levels of interferon.
REFERENCES:
patent: 2851453 (1958-09-01), Kennon
patent: 3066075 (1962-11-01), Deutsch
patent: 3493559 (1970-03-01), Hunter
patent: 3821193 (1974-06-01), Fare et al.
patent: 3843629 (1974-10-01), Sheit et al.
patent: 3845033 (1974-10-01), Harnden
patent: 3853846 (1974-12-01), Prasad et al.
Matsuo et al.: Bull. Chem. Soc. Japan, 39, 347-352, (1966).
Bretscher: Chem. Abstr., 60:8261h (1964).
Gotts Lewis
Suyat Reginald J.
The United States of America as represented by the Department of
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