Nuclear targeting by means of bacterial proteins

Details Nuclear targeting by means of bacterial proteins Nuclear targeting by means of bacterial proteins

2007-02-13

2007-02-13

Duffy, Patricia A. (Department: 1645)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S04400A, C530S350000, C530S820000, C424S192100, C424S193100, C424S197110

Reexamination Certificate

active

09569349

ABSTRACT:
A nuclear delivery construct comprises (i) protein H or a fragment or derivative thereof that is capable of being targeted to the nucleus of a eukaryotic cell; and associated therewith (ii) one or more other components whose targeting to the nucleus of the eukaryotic cell is desired.

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Wimg id="CUSTOM-CHARACTER-00001" he="2.79mm" wi="2.12mm" file="US07176178-20070213-P00001.TIF" alt="custom character" img-content="character" img-format="tif" ?sierska-Gimg id="CUSTOM-CHARACTER-00002" he="2.79mm" wi="2.12mm" file="US07176178-20070213-P00002.TIF" alt="custom character" img-content="character" img-format="tif" ?dek et al., “Nucleolar Proteins B23 and C23 as Target Antigens in Chronic Graft-Versus-Host Disease,”Blood 79(4): 1081-1086, 1992.

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