Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-06-07
1998-12-15
Scheiner, Toni R.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 71, 436 64, 436813, G01N 33574, G01N 3353
Patent
active
058495096
ABSTRACT:
Nuclear matrix proteins (NMP) which are characterized by a defined expression in tissue are provided. These NMPs are useful markers in diagnosing and monitoring the stage of malignancy of a cell. Also provided are substantially purified polypeptides and nucleotide sequences encoding the NMPs of the invention.
REFERENCES:
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Cupo, J.F. (1991) J. Chromatog. 569:389-406.
Getzenberg & Coffey (1990). Molec Endocr. 4:1336-42.
Getzenberg et al. (1991) Biochem. Biophys. Res. Comm. 179:340-44.
Getzenberg et al. (1991) Cancer Res 51:6514-20.
Partin & Coffey (1994) Rec Prog Houm Res. 49:293-331.
Coffey Donald S.
Getzenberg Robert H.
Partin Alan W.
Scheiner Toni R.
The Johns Hopkins University School of Medicine
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