Nuclear magnetic resonance spectroscopy

Electricity: measuring and testing – Particle precession resonance – Using a nuclear resonance spectrometer system

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G01R 3308

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active

046895612

ABSTRACT:
The present invention provides a nuclear magnetic resonance spectroscopy that permits one to see changes in spectra without the use of long-range coupling even if the obtained resonance lines split into complex multiplet patterns. The spectrometry comprises the steps of: (a) applying a pulse train of radio-frequency irradiation to a nucleus under observation; (b) applying weak radio-frequency irradiation having a frequency equal to the resonance frequency either of an unobserved nucleus coupled to the observed nucleus or of the observed nucleus in synchronism with the application of the pulse train; (c) receiving the free induction decay signal produced after the application of the pulse train and storing it in a memory; (d) applying a pulse train of radio-frequency irradiation to the observed nucleus; (e) receiving the free induction decay signal produced after the application of the pulse train in step (d) and either adding it to the free induction decay signal stored in step (c) or substracting it from the previously stored signal; and (f) taking the Fourier transform of the free induction decay signal obtained by the arithmetic operation in step (e).

REFERENCES:
Seto, H. et al, "Structure Analysis of Natural Products by Nuclear Magnetic Resonance Spectroscopy", JEOL News, Analytical Instrumentation, vol. 21, No. 1, Feb. 15, 1985.
"Application of Long Range J C--H Resolved 2d Spectroscopy (LRJR) in Structural Elucidation of Natural Products, The Structure of Oxirapentyn, (Reprint from Tetrahedron Letters, vol. 25, No. 3, pp. 337-340), by H. Seto et al.

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