Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent
Patent
1991-01-22
1997-12-30
Kight, John
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Magnetic imaging agent
534 10, 534 15, 534 16, 436173, A61B 5055, C07F 500, G01N 2400
Patent
active
057026831
ABSTRACT:
A family of contrast agents for use in magnetic resonance imaging and a method of enhancing the contrast of magnetic resonance images of an object by incorporating a contrast agent of this invention into the object prior to forming the images or during formation of the images. A contrast agent of this invention is a paramagnetic lanthanide hexaazamacrocyclic molecule, where a basic example has the formula LnC.sub.16 H.sub.14 N.sub.6. Important applications of the invention are in medical diagnosis, treatment, and research, where images of portions of a human body are formed by means of magnetic resonance techniques.
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Brainard James R.
Jarvinen Gordon D.
Ryan Robert R.
Smith Paul H.
Cordovano Richard J.
Freund Samuel M.
Hartley Michael G.
Kight John
Moser William R.
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