Nuclear autoantigen

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Nucleoproteins – e.g. – chromatin – chromosomal proteins,...

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530350, 530403, 436508, 935 71, A61K 3710, G01N 3353, C07K 1506, C07K 1702

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active

052722562

ABSTRACT:
The invention relates to a Ge protein having an apparent molecular weight of 170 kilodaltons when derived from HeLa cells. The Ge protein is a nuclear autoantigen that may be used to detect autoimmune disorders, such as Sjogren's syndrome, which is characterized by the presence of antinuclear antibodies binding to the Ge protein.

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