Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Patent
1997-11-13
1999-11-30
Harrison, Robert H.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
424451, 424452, 424464, 424465, 514922, 514951, 514960, 514974, A61K 916, A61K 4730, A61K 4736
Patent
active
059938609
ABSTRACT:
An oral-delivery pharmaceutical composition for reducing the gastric irritation effect of an NSAID in the upper GI tract of a mammal. The composition includes (a) a mucosal protective amount of a pharmaceutically-acceptable hydrocolloid gum obtainable from higher plants, (b) a dispersion-enhancing amount of another excipient and (c) a therapeutically-effective amount of an NSAID. Also disclosed is a process for preparing the composition and a method for reducing the gastric irritation effect of the NSAID by administering the composition. Also, disclosed is a composition particularly useful for preparing an aqueous suspension.
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Friend David R.
Kuhrts Eric H.
Parasrampuria Jagdish
Yu Karen
Harrison Robert H.
Venture Lending
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