NPY Y5 antagonist

Details NPY Y5 antagonist NPY Y5 antagonist

2007-09-04

2007-09-04

Chang, Celia (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S309000, C514S313000, C514S367000, C514S377000, C514S403000, C514S415000, C514S443000, C514S452000, C514S456000, C514S464000, C514S529000, C514S602000, C514S603000, C546S159000, C546S141000, C546S143000, C548S162000, C548S222000, C548S365700, C548S483000, C549S057000, C549S362000, C549S398000, C549S434000, C564S080000, C564S082000, C564S090000, C564S092000, C560S125000

Reexamination Certificate

active

10747359

ABSTRACT:
The present invention provides a pharmaceutical composition for use as an NPY Y5 receptor antagonist comprising a compound of the formula (I):wherein R1is lower alkyl, cycloalkyl or the like,R2is hydrogen, lower alkyl or the like,n is 1 or 2,X is lower alkylene, lower alkenylene, arylene, cycloalkylene or the like,Y is CONR7, CSNR7, NR7CO, NR7CS or the like,Z is lower alkyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl or the like and R7is hydrogen or lower alkyl,prodrug, pharmaceutically acceptable salt or solvate thereof.

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