Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Lipid or oil
Patent
1977-02-22
1978-03-07
Milestone, Norma S.
Drug, bio-affecting and body treating compositions
Nonspecific immunoeffector, per se ; or nonspecific...
Lipid or oil
260308D, 260335, C07D31186
Patent
active
040780783
ABSTRACT:
Novel xanthone-2-carboxylic acid compounds of the formula ##STR1## wherein A is selected from the group consisting of --COOR', a 1H-tetrazol-5-yl and a 1H-tetrazolylcarbamoyl, R' is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms and cation of a non-toxic, pharmaceutically acceptable organic or inorganic base, R is selected from the group consisting of hydrogen, alkyl of 1 to 9 carbon atoms, alkoxy of 1 to 9 carbon atoms and alkoxy alkoxy of 2 to 9 carbon atoms and X is selected from the group consisting of ##STR2## AND ##STR3## WHEREIN R.sub.1 is alkyl of 1 to 5 carbon atoms, R.sub.2 is selected from the group consisting of hydrogen, acyl of an aliphatic acid of 1 to 5 carbon atoms, aroyl of 7 to 8 carbon atoms, araliphatic acyl with 1 to 5 carbon atoms in the aliphatic portion and 6 or 7 carbon atoms in the aryl portion, aralkyl of 7 to 8 carbon atoms, arylsulfonyl, a carbamoyl, a carboxyalkyl of 1 to 5 carbon atoms, --CO--(CH.sub.2).sub.n -- Het where n is 1,2 or 3 and Het is a N-attached nitrogen heterocyclic which may contain an additional heteroatom and ##STR4## AND Alk is alkyl of 1 to 5 carbon atoms and R.sub.3 is arylsulfonyl which possess anti-allergic properties and their preparation.
REFERENCES:
patent: 3849565 (1974-11-01), Pfister et al.
Barnes Alan Charles
Hairsine Peter Wilfred
Ramm Peter John
Taylor John Bodenham
Milestone Norma S.
Roussel Uclaf
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