Novel vitamin E derivatives and process for the production there

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546256, 549410, A61K 31455, C07D40514

Patent

active

051028956

ABSTRACT:
The novel vitamin E derivative provides an excellent antihyperlipemic effect and is defined by the formula (I): ##STR1## wherein R represents a nicotinoyl group; and m is an integer of from 2 to 5 while n is an integer of from 3 to 6, provided that n is larger than m.

REFERENCES:
Sundaram et al. Lipids, vol. 16, No. 4, pp. 223-227 (1981).
Paul et al., "Effect of Vitamin E on Lipid Components of Atherogenic Rats", Internat. J. Vit. Nutr. Res., vol. 59, pp. 35-39 (1989).

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