Novel vaginal suppository

Drug – bio-affecting and body treating compositions – Lymphokine

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Details

424433, 514397, 514967, A61K 3179, A61K 31415, A61K 902

Patent

active

047659785

ABSTRACT:
An antifungal vaginal suppository is disclosed comprising cis-2-(1H-imidazolylmethyl)-3-(2',6'-difluorobenzyloxy)-2,3-dihydro-5-fluo robenzo[b]thiophene in a suppository base containing biocompatible polymers, a surfactant and an absorbent in a vegetable oil phase.

REFERENCES:
patent: 4352808 (1982-10-01), Rane et al.
patent: 4542020 (1985-09-01), Jackson et al.
Mycelex-G 500 mg Vaginal Tablet, Miles Pharm., 1980, package insert.
The Theory and Practice of Industrial Pharmacy, 2nd Ed., 1976, Lachman et al., Chap. 8 "Suppositories," pp. 245-273.

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