Novel tricycloundecane aminoacid amide

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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424267, 424274, 424320, 544154, 546192, 2603262, 564164, 564165, 564193, A61K 3116, C07C 8740, C07C10300

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active

042725364

ABSTRACT:
A compound having the formula ##STR1## wherein a is 0 or 1, R.sub.1 is hydrogen or lower alkyl, A is lower alkylene or lower alkylidene, and R.sub.2 and R.sub.3, which can be the same or different, are hydrogen, lower alkyl, cycloalkyl, benzyl or substituted benzyl, or ##STR2## form a saturated heterocyclic ring, and pharmacologically acceptable acid addition salt thereof, exhibits anti-viral activity and is free from significant effect on the central nervous system.

REFERENCES:
patent: 3985803 (1976-10-01), Inamoto et al.
patent: 4104305 (1978-08-01), Inamoto et al.
Koji et al., Chem. Abstracts, vol. 90, abst. 203,565u (1979) (abst. of Japan Kokai 79-14,953, Feb. 3, 1979).
Koji et al., Chem. Abstracts, vol. 90, abst. 203,567w (1979) (abst. of Japan Kokai 79-14,955, Feb. 3, 1979).
Inamoto et al., Chem. Abstracts, vol. 89, abst. 42588r (1978) (abst. of Ger. Offen. 2,745,414, Apr. 2, 1978).

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