Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1975-04-10
1976-02-17
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
424319, A61K 3124, A61K 31195
Patent
active
039392538
ABSTRACT:
There is provided, novel, transient pro-drug forms of L-DOPA (3,4-dihydroxy-L-phenylalanine), having the formula: ##SPC1##
Wherein R represents a member selected from the group consisting of a hydrogen atom, a --COCH.sub.3 group, a --COC.sub.2 H.sub.5 group, a --COOC.sub.2 H.sub.5 group, and a --CO--C(CH.sub.3).sub.3 group; wherein R.sub.1 represents a member selected from the group consisting of a hydroxyl group, a --OM group (wherein M represents an alkali metal or an ammonium ion), a --OCH.sub.2 --C.sub.6 H.sub.5 group, a --OCH.sub.3 group, a --OC.sub.2 H.sub.5 group, and --NH--CH(R.sub.3)COOH group, wherein R.sub.3 represents the residue of any naturally occurring amino acid; and wherein R.sub.2 represents a member selected from the group consisting of a hydrogen atom, a formyl group, a --CO--C.sub.6 H.sub.5 group, a --CO--pyridyl group, a --CO(R.sub.5)--CH=CH(R.sub.4) group, and a NH.sub.2 --CH(R.sub.6)--CO-- group, wherein R.sub.4 represents a methyl group and wherein R.sub.5 represents a member selected from the group consisting of a methyl group, a --OC.sub.2 H.sub.5 group, and a C.sub.6 H.sub.5 -- group, and wherein R.sub.6 represents the residue of any naturally occurring amino acid,
With the proviso that simultaneously,
Bodor Nicolae S.
Hussain Anwar A.
Sloan Kenneth B.
Blitzer Charles N.
Friedman Stanley J.
Interx Research Corporation
LandOfFree
Novel, transient pro-drug forms of l-dopa useful in the treatmen does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel, transient pro-drug forms of l-dopa useful in the treatmen, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel, transient pro-drug forms of l-dopa useful in the treatmen will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1746940