Novel, transient pro-drug forms of L-DOPA

Details Novel, transient pro-drug forms of L-DOPA Novel, transient pro-drug forms of L-DOPA

1975-04-17

1976-12-21

Gotts, Lewis

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424177, C07C10352, A61K 3700

Patent

active

039987990

ABSTRACT:
There is provided, novel, transient pro-drug forms of L-DOPA (3,4-dihydroxy-L-phenylalanine), having the formula: ##STR1## wherein n represents an integer of from 2 to 50 with respect to formula (V-A), and wherein n represents an integer of from 1 to 50 with respect to formula (V-B);
R represents a hydrogen atom, an acyl group, ##STR2## --CO-pyridyl, or --CO--R.sub.3, wherein R.sub.3 is the residue of any N,N-C.sub.1 -C.sub.2 dialkylamino acid or a C.sub.4 -C.sub.6 cycloalkylamino acid; R.sub.1 represents --OH, --O-lower alkyl, --O-benzyl, or a naturally occurring protein amino acid; and R.sub.2 represents ##STR3## --CO-pyridyl, a naturally occurring protein amino acid, 3',4'-L-diacyloxy phenylalanine, or --CO-R.sub.3.
These compounds are all useful in the treatment of Parkinson's Disease.

REFERENCES:
patent: 3803120 (1974-04-01), Felix
patent: 3891696 (1975-06-01), Bodor et al.

Affiliated with

Also associated with

Rating

Novel, transient pro-drug forms of L-DOPA does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Novel, transient pro-drug forms of L-DOPA, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel, transient pro-drug forms of L-DOPA will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1838249