Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...
Patent
1987-10-05
1989-06-13
Robinson, Ellis P.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Web, sheet or filament bases; compositions of bandages; or...
424448, 424486, 424449, 131335, 128156, 128632, A61L 1500, A61B 500
Patent
active
048391743
ABSTRACT:
A controlled release transdermal delivery system for nicotine administration. The system comprises an impermeable backing layer, a polyurethane matrix layer containing between about 5 wt % and 50 wt % nicotine, and an adhesive skin-contacting layer. The system is designed to administer nicotine for smoking cessation therapy or other uses over a period of 24 hours or more.
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J. E. Rose et al., "Transdermal Administration of Nicotine", Drug and Alcohol Dep., 13, 209-213, 1984.
J. F. Komerska, "Urethane Films--Transdermal Opportunities", J. Plastic Film and Sheeting, 3, 58-64, 1987.
Baker Richard W.
Huang Carl
Kochinke Frank
Farrant J.
Pharmetrix Corporation
Robinson Ellis P.
Ryan P. J.
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