Novel (trans 1-propenyl)disulfide derivative and process for pre

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters

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556 94, 556428, 558104, 562598, 549307, C07C32100, C07F 708, C07F 902

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active

050119753

ABSTRACT:
A (trans 1-propenyl)disulfide derivative having a distinguished anti-tumor effect, represented by the following general formula: ##STR1## , wherein R is a lower alkylene group and R' is a hydrogen atom or a carboxyl protective group, is prepared by allowing a carboxylic acid thiol derivative, represented by the following general formula:

REFERENCES:
patent: 4438270 (1984-03-01), Bey et al.
Proceedings of AACR, vol. 27, p. 140, Mar. issue, 1986.

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