Novel topically administrable pharmaceutical compositions

Details Novel topically administrable pharmaceutical compositions Novel topically administrable pharmaceutical compositions

1989-08-21

1990-04-17

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Lymphokine

A61K 3178

Patent

active

049178865

ABSTRACT:
Novel topically administrable pharamceutical composition containing, as active ingredient, from approximately 0.1 to approximately 10% by weight of a non-steroidal, anti-inflammatorially active compound having at least one acidic group, from approximately 10 to approximately 50% by weight of a water-soluble, volatile lower alkanol having from 2 up to and including 4 carbon atoms, from approximately 3 to approximately 15% by weight of an optionally self-emulsifying lipid or a mixture of lipids, from approximately 0.5 to approximately 2% by weight of a gel structure former, from approximately 1 to approximately 20% by weight of a co-solvent, from approximately 40 to approximately 80% by weight of water, optionally from approximately 0.5 to approximately 5% by weight of an emulsifier if the lipid phase is not self-emulsifying and, if desired, non-essential constituents.

REFERENCES:
patent: 3629412 (1971-12-01), Silber et al.
patent: 3749773 (1973-07-01), Ninger
patent: 4309414 (1982-01-01), Inagi et al.
patent: 4390532 (1983-06-01), Stuttgen et al.
patent: 4525347 (1985-06-01), Inagi et al.
patent: 4551475 (1985-03-01), Eckert
patent: 4807824 (1983-01-01), Eckert
American Heritage Dictionary-New College Edition, (1976), pp. 262, 429 and 547.
Eric W. Martin, Dispensing of Medication, 7th Edition, (1971), pp. 533 & 534.
PCT WO81/02673.
PCT/WO81/00206.
Chem. Abstr. 95:103322x (5/81), p. 357.
Patent Abstract of Japan, vol. 5, No. 111 (C-63) [783], 1981,

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