Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1984-06-11
1986-05-06
Gerstl, Robert
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548147, C07D51310, C07D27760, A61K 31425
Patent
active
045872562
ABSTRACT:
The invention relates to with novel thiazolidine derivatives of the formula ##STR1## wherein X is methylene, oxygen or sulfur; R.sup.1 is halogen; R.sup.2 is hydrogen, nitro, cyano, OR.sup.3 or NHR.sup.3 ; or R.sup.1 and R.sup.2 both simultaneously are hydrogen or nitro; R.sup.3 is hydrogen, alkyl, acyl, --CO--OR.sup.4 or --CO--NHR.sup.4 ; and R.sup.4 is alkyl, unsubstituted or substituted aryl or aralkyl,
and their salts with physiologically compatible cations. The compounds of formula I are useful in the treatment of metabolic disorders.
REFERENCES:
Sohda et al., Chem. Pharm. Bull. 30 3601 (1983).
Hasler Heinz
Schneider Fernand
Gerstl Robert
Hoffmann-La Roche Inc.
Isgro William G.
Leon Bernard S.
Saxe Jon S.
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