Novel tetrahydrocannabinol type compounds

Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Lipid or oil

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Details

2603453, A61K 3135, C07D31102

Patent

active

041795172

ABSTRACT:
A pharmaceutical composition of matter substantially devoid of "cannabis-e" CNS activity containing as active ingredient a compound of the formula ##STR1## wherein A-----B designates a 1(2) or a 6(1) double bond and wherein R' designates --H or --CO--R where R is lower alkyl, and R" designates alkyl and novel compounds of the 3S,4S configuration of the formula ##STR2## wherein A----B designates a 1(2) or a 6(1) double bond, R' designates hydrogen or --CO--R where --R is lower alkyl, and R" designates alkyl of at least 6 carbon atoms.

REFERENCES:
patent: 4025516 (1977-05-01), Razdan et al.
Mechoulam et al., JACS, 94, 6159 (1972).
Jen et al., JACS, 89, 4551 (1967).
Mechoulam et al., JACS, 89, 4552 (1967).
Mechoulam et al., JACS, 87, 3273 (1965).
Yaoni et al., JACS, 86, 1646 (1964).
Fahrenholtz et al., JACS, 89, 5934 (1967).
Taylor et al., JACS, 88, 367 (1966).

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