Novel synthesis of 3-amino-2-methylbenzotrifluoride and the inte

Details Novel synthesis of 3-amino-2-methylbenzotrifluoride and the inte Novel synthesis of 3-amino-2-methylbenzotrifluoride and the inte

1977-06-10

1979-10-23

Douglas, Winston A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260582, C07C 8520, C07C 8524, C07C 8526

Patent

active

041720954

ABSTRACT:
This invention relates to a novel process for preparing 3-amino-2-methylbenzotrifluoride from 4-X-substituted-2-methylthiomethylbenzotrifluorides. The former compounds are useful in the preparation of anilino-nicotinic and anilino-anthranilic acids exhibiting analgesic, anti-inflammatory or anti-diarrheal properties. Some of the intermediates are novel per se.

REFERENCES:
patent: 3894034 (1975-07-01), Gassman et al.
Claus, et al., "Tetrahedron Letters", No. 32, pp. 3607-3610 (1968).

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