Novel supports carrying side chains, processes for obtaining the

Details Novel supports carrying side chains, processes for obtaining the Novel supports carrying side chains, processes for obtaining the

1980-09-30

1983-12-06

Kepplinger, Esther M.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435174, 435176, 435178, 435179, 435180, 435181, 435188, 536 11, 260112R, 260121, 436518, 436527, 436529, 436530, 436531, 436532, 436533, G01N 3350, C12N 1100, C12N 1106, C12N 1108, C12N 1110, C12N 1112, C12N 1114

Patent

active

044194447

ABSTRACT:
Process for chemically binding organic compounds containing carbohydrate residues, onto a support bearing at least one reactive --NH.sub.2, in which at least one --CH.sub.2 OH group of the carbohydrate residue is transformed in a --CHO group, by oxidation and then the --CHO groups thus obtained are reacted with at least a reactive --NH.sub.2 carried by the side chains covalently bound on a solid, insoluble support, the side chains are chosen from among amines, polyamines, diacids, amino-acids, hydrazines, and are eventually coupled, by the intermediary of their reactive --NH.sub.2, with a nitrogen-containing compound chosen from aliphatic or aromatic amines, aliphatic or aromatic hydrazines, or amino acids, comprising eventually jointly a --SH group and a --NH.sub.2 group.
Products resulting from this process and biological reagents containing said products as their active constituents.

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Ray, et al., "Differential Release of Sialic Acid from Normal and Malignant Cells by Vibrio Cholerae Neuramindase or Influenza Virus Neuramindase", Chem. Abstracts, vol. 79, No. 8, p. 52 (1973) Abs. No. 49543z.
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