Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Tripeptides – e.g. – tripeptide thyroliberin – etc.
Patent
1985-05-09
1986-11-11
Phillips, Delbert R.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Tripeptides, e.g., tripeptide thyroliberin , etc.
530802, 435 13, C07K 508, C12Q 156
Patent
active
046223894
ABSTRACT:
A novel chromogenic and fluorescent substrate for determining the activity of blood coagulation factor Xa and Xa-like enzymes. The novel substrate according to the present invention has very excellent selectivity as compared with the hitherto disclosed substrates and enables specific determination of blood coagulation factor Xa. The present substrate is therefore useful for the studies of chemical reactions involving formation, inhibition and consumption of factor Xa and can be also used for the determination of various factors associated therewith such as factor X, anti-Xa factor, factor VII, factor VIII, factor IX and heparin.
REFERENCES:
patent: 4452736 (1984-06-01), Nagasawa et al.
Enomoto Tsuyoshi
Kuroiwa Katsumasa
Nagasawa Takeshi
Nakamura Yoshio
Lewen Bert J.
Nitto Poseki Co., Ltd.
Phillips Delbert R.
Sternberg Henry
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