Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1980-12-17
1982-08-24
Trousof, Natalie
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
424319, 424324, 562444, 560 39, 564157, C07C101447, A61K 3124, A61K 31195, C07C10329
Patent
active
043461050
ABSTRACT:
Phenylacetic acid amide compounds of the formula ##STR1## in which R.sub.1 is hydrogen, lower alkyl, lower alkoxy, halogen having an atomic number of not more than 35 or trifluoromethyl, R.sub.2 is hydrogen, lower alkyl, lower alkoxy, halogen having an atomic number of not more than 35 or trifluoromethyl, R.sub.3 is hydrogen, lower alkyl, lower alkoxy or halogen having an atomic number of not more than 35 and R.sub.4 is hydrogen, lower alkyl, lower alkoxy or halogen having an atomic number of not more than 35, and in which R.sub.5 is a radical of aliphatic character containing the group R.sub.6, R.sub.6 and R.sub.7 are each hydrogen or together are a divalent aliphatic radical and the group of the formula --C(.dbd.O)--R.sub.8 (Ia) is a carboxyl group, which can be functionally modified, and their salts are useful as anti-inflammatory agents.
REFERENCES:
patent: 3536758 (1970-10-01), Sallmann et al.
patent: 3652762 (1972-03-01), Sallmann
patent: 3897782 (1975-07-01), Boltye et al.
patent: 4143151 (1979-05-01), Wagner et al.
Baschang Gerhard
Sallmann Alfred
Ciba-Geigy Corporation
Glynn Michael W.
Gruenfeld Norbert
Reamer James H.
Trousof Natalie
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