Novel substituted N-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides

Details Novel substituted N-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides Novel substituted N-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides

1988-09-02

1990-12-04

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546221, 546 15, 546188, 546194, 546208, 546209, 546210, 540524, 540544, 540553, 540597, 544 584, 544130, 544310, 544316, 544360, 544 52, 544105, 544355, 514211, 514212, 514218, 5142278, 5142355, 514252, 514256, 514274, 514278, 514318, 514326, 514327, 5142305, 5142242, 514249, A61K 3138, A61K 31445, C07D21122, C07D28102, C07D26702

Patent

active

049754394

ABSTRACT:
Substituted N-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides, their N-oxide forms, their pharmaceutically acceptable acid addition salts and stereochemically isomeric forms having gastrointestinal motility stimulating properties, compositions containing the same, and methods of treating warm-blooded animals suffering from motility disorders of the gastrointestinal system.

REFERENCES:
Schuurkes et al., J. E. Pharm. & Therapeutics, vol. 234, No. 3, (1985), pp. 775-783.
Van Daele et al., Chemical Abstracts, vol. 99, 1983, 99:194812d; p. 740.

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