Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1990-02-07
1991-08-20
Richter, Johann
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
558414, 558417, 560251, 564153, 564155, 564157, 514546, 514552, 514616, 514329, 5142382, 544163, 544164, A61K 31275, A61K 31165, C07C25550, C07C23316
Patent
active
050414623
ABSTRACT:
Novel substituted acetamide compounds of the formula ##STR1## wherein R.sup.1 is hydrogen atom, a lower alkyl group, a lower acyl group, or an aryl group; R.sup.2 is cyano group or aminocarbonyl group; R.sup.3 is a halogen atom, nitro group, a lower alkoxy group, a group of the formula: --NR.sup.4 R.sup.5 (wherein R.sup.4 is hydrogen atom, a lower alkyl group or a group of the formula: --COCH.sub.2 OR.sup.1 ; R.sup.5 is hydrogen atom or a lower alkyl group), or a cyclic amino group of the formula: ##STR2## (wherein R.sup.6 and R.sup.7 are each an alkylene group having 1 to 3 carbon atoms, and X is oxygen atom or methylene), or a pharmaceutically acceptable acid addition salt thereof, which have excellent anti-allergic activity and are useful for the prophylaxis and treatment of various allergic diseases, and a pharmaceutical composition containing the amide compound as set forth above as an active ingredient.
REFERENCES:
patent: 3867437 (1975-02-01), Fujimura
Ban Masakazu
Katsushima Takeo
Shinoda Kiyotaka
Taguchi Hiroaki
Takahashi Mitsuru
Richter Johann
Toyo Boseki Kabushiki Kaisha
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