Novel substituted acetamide compounds and use as anti-allergic a

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai

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558414, 558417, 560251, 564153, 564155, 564157, 514546, 514552, 514616, 514329, 5142382, 544163, 544164, A61K 31275, A61K 31165, C07C25550, C07C23316

Patent

active

050414623

ABSTRACT:
Novel substituted acetamide compounds of the formula ##STR1## wherein R.sup.1 is hydrogen atom, a lower alkyl group, a lower acyl group, or an aryl group; R.sup.2 is cyano group or aminocarbonyl group; R.sup.3 is a halogen atom, nitro group, a lower alkoxy group, a group of the formula: --NR.sup.4 R.sup.5 (wherein R.sup.4 is hydrogen atom, a lower alkyl group or a group of the formula: --COCH.sub.2 OR.sup.1 ; R.sup.5 is hydrogen atom or a lower alkyl group), or a cyclic amino group of the formula: ##STR2## (wherein R.sup.6 and R.sup.7 are each an alkylene group having 1 to 3 carbon atoms, and X is oxygen atom or methylene), or a pharmaceutically acceptable acid addition salt thereof, which have excellent anti-allergic activity and are useful for the prophylaxis and treatment of various allergic diseases, and a pharmaceutical composition containing the amide compound as set forth above as an active ingredient.

REFERENCES:
patent: 3867437 (1975-02-01), Fujimura

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