Novel substances having antitumor and immunostimulating activity

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide

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435 84, 435128, 435253, 435822, 514 8, 514 23, 530350, 530351, C12P 2100, C12P 1926, C12N 120, A61K 3700

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active

045915580

ABSTRACT:
Novel TF-2 substances having antitumor and immunostimulating activity, which are obtained from a culture or its supernatant fluid prepared by culturing bacteria belonging to Fusobacterium genus. Said substances are useful for the treatment of cancerous diseases of the mammals including human beings. This disclosure concerns such substances and a process for preparing the same and an antitumor agent containing the same.

REFERENCES:
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patent: 4357323 (1982-11-01), Soma et al.
patent: 4477437 (1984-10-01), Tomac et al.
Rietschel, Chem. Absts., vol. 85 (1976), p. 188, Absts. #88,869(d).
Falkler et al, Chem. Absts., vol. 92 (1980), p. 125, Absts. #122,508(s).
Mongiello et al, Chem. Absts., vol. 92 (1980), p. 125, Absts. #122,509(t).

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