Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...
Patent
1978-09-08
1982-01-12
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugated via claimed linking group, bond, chelating agent,...
435 76, 435119, 435253, 26034341, 536 17R, A61K 3171, C07H 1708
Patent
active
043105190
ABSTRACT:
Novel compounds are produced by the fermentation of a nutrient medium with the previously undescribed microorganism Streptomyces avermitilis. They may be isolated by solvent extraction and chromatographic fractionation techniques. The compounds, which are described generically as C-076 have significant parasiticidal activity. The compounds may be included in compositions for the oral or parenteral administration to animals for the treatment of parasitic infections.
REFERENCES:
patent: 3950360 (1976-04-01), Aoki et al.
patent: 4134973 (1979-01-01), Fisher et al.
patent: 4160083 (1979-07-01), Cole
patent: 4160084 (1979-07-01), Miller et al.
patent: 4160861 (1979-07-01), Cole et al.
patent: 4161583 (1979-07-01), Wilson et al.
Mishima et al., "Tetrahedron Letters", vol. 10, pp. 711-714, 1975.
Derwent Abstract 76268w/46 to Sankyo Co. Ltd.
Albers-Schonberg George
Burg Richard W.
Miller Thomas W.
Ormond Robert E.
Wallick Hyman
Brown Johnnie R.
Merck & Co. , Inc.
Rose David L.
Westlake Harry E.
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