Novel substance DC 113 and production thereof

Details Novel substance DC 113 and production thereof Novel substance DC 113 and production thereof

1989-12-28

1992-03-31

Ceperley, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

435119, 514410, C07D48704, A61K 3140

Patent

active

051010380

ABSTRACT:
A novel fermentation product, DC113, represented by the formula ##STR1## which has antimicrobial and antitumor activities.

REFERENCES:
patent: 4169888 (1979-10-01), Hanka et al.
patent: 4400518 (1983-08-01), Wierenga
patent: 4413132 (1983-11-01), Wierenga
patent: 4423228 (1983-12-01), Wierenga
patent: 4423229 (1983-11-01), Wierenga
patent: 4423230 (1983-12-01), Wierenga
Adv. Enzyme Regulation, Wierenga, et al. "Antitumor Activity and Biochemistry of Novel Analogs of the Antibiotic, CC-1065", vol. 22, p. 141 (1986).
J. Medicinal Chemistry, Warpehoski, M. A. et al., "Stereoelectronic Factors Influencing the Biological Activity and DNA Interaction of Synthetic Antitumor Agents Modeled on CC-1065," vol. 31, No. 3, p. 590 (1988).

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