Novel steroids

Details Novel steroids Novel steroids

1978-06-15

1980-03-04

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26023955R, 26039745, C07J 100

Patent

active

041916972

ABSTRACT:
Novel .DELTA..sup.1,3,5(10),6 -estratetraenes of the formula ##STR1## R is selected from the group consisting of hydrogen, acyl of an alkanoic acid of 1 to 5 carbon atoms, optionally substituted benzoyl, tetrahydropyranyl, trityl and trimethylsilyl and R.sub.1 is selected from the group consisting of acyl of an alkanoic acid of 1 to 5 carbon atoms, optionally substituted benzoyl, tetrahydropyranyl, trityl and trimethylsilyl, novel intermediates therefore, process for the preparation of estradiols marked with a tritium atom and the novel tritiated estradiols which are useful to the study and dosage of specific receptors of estrogen.

REFERENCES:
patent: 3526648 (1970-09-01), Bertin et al.
patent: 3579545 (1971-05-01), Bertin et al.
"Steroid Drugs," by Applezweig, pp. 442-443, 448-449.
J.A.C.S., vol. 72 (1950), p. 4540 article by Djerassi et al.
"Steroids" (1974) article by Kundu, pp. 155-163.

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