Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-03-21
1992-03-17
Chan, Nicky
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549363, A61K 31335, C07D31908
Patent
active
050969234
ABSTRACT:
This invention relates to compounds of structural formula (I): ##STR1## which are squalene synthetase inhibitors and thus useful as cholesterol lowering agents.
REFERENCES:
patent: 4871721 (1989-10-01), Biller
S. A. Biller et al., J. Med. Chem., 31, 1869 (1988).
C. D. Poulter et al., J. Am. Chem. Soc., 111, 3734 (1989).
E. J. Corey et al., J. Am. Chem. Soc., 98, 1291 (1976).
Bergstrom James D.
Hensens Otto D.
Huang Leeyuan
Liesch Jerrold M.
Onishi Janet C.
Chan Nicky
DiPrima Joseph F.
Merck & Co. , Inc.
Winokur Melvin
LandOfFree
Novel squalene synthetase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel squalene synthetase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel squalene synthetase inhibitors will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1476185