Novel spergualin-related compounds and process for producing the

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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2604045, 562439, 562556, 562560, 530331, 548537, 548344, 548496, 548518, C07C12912

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active

049565044

ABSTRACT:
The present invention relates to novel Spergualin-related compounds represented by the general formula [I] ##STR1## (wherein X is ##STR2## R is --H or --CH.sub.2 OH; R.sub.1 is --H, ##STR3## R.sub.2 is a residue obtained by removing, from an amino acid or peptide, the hydroxyl group of the carboxyl group and, when R.sub.1 is a group other than --H, R.sub.2 is same as R.sub.1), or a pharmacologically acceptable salt thereof. Said compounds or salts thereof have an immuno-modulating action.

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Umezawa et al., 13th International Congress of Chemotherapy (1983), pp. 76-77.
Takekuchi et al., The Journal of Antibiotics, vol. 34, No. 12 (1981), pp. 1619-1627.
Umezawa et al., The Journal of Antibiotics, vol. 38, No. 2 (1985), pp. 283-284.
Umeda et al., The Journal of Antibiotics, vol. 38, No. 7 (1985), pp. 886-898.

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